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Interaction of cyclosporin derivatives with the ATPase activity of human P-glycoprotein
1. P-glycoprotein, a 170–180 kDa membrane glycoprotein that mediates multidrug resistance, hydrolyses ATP to efflux a broad spectrum of hydrophobic agents. In this study, we analysed the effects of three MDR reversing agents, verapamil, cyclosporin A and [3′-keto-Bmt]-[Val(*)]-cyclosporin (PSC 833),...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
1997
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564934/ https://ncbi.nlm.nih.gov/pubmed/9313931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701377 |
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