Cyclosporin A Enhances Susceptibility of Multi‐drug Resistant Human Cancer Cells to Anti‐P‐glycoprotein Antibody‐dependent Cytotoxicity of Monocytes, but Not of Lymphocytes

Cyclosporin A (CsA) was previously found to bind to P‐glycoprotein expressed on multidrug‐resistant (MDR) cancer cells. In the present study, the effect of CsA on anti‐P‐glycoprotein monoclonal antibody (mAb)‐dependent cell‐mediated cytotoxicity (ADCC) against human MDR cells was examined. The ADCC...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Yano, Seiji, Sone, Saburo, Nishioka, Yasuhiko, Naito, Mikihiko, Tsuruo, Takashi, Ogura, Takeshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 1994
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919430/
https://ncbi.nlm.nih.gov/pubmed/7511575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1994.tb02082.x
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