Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics

Prioritizing the risk posed by thousands of chemicals potentially present in the environment requires exposure, toxicity, and toxicokinetic (TK) data, which are often unavailable. Relatively high throughput, in vitro TK (HTTK) assays and in vitro-to-in vivo extrapolation (IVIVE) methods have been de...

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Bibliografische gegevens
Gepubliceerd in:Toxicol Sci
Hoofdauteurs: Wambaugh, John F, Hughes, Michael F, Ring, Caroline L, MacMillan, Denise K, Ford, Jermaine, Fennell, Timothy R, Black, Sherry R, Snyder, Rodney W, Sipes, Nisha S, Wetmore, Barbara A, Westerhout, Joost, Setzer, R Woodrow, Pearce, Robert G, Simmons, Jane Ellen, Thomas, Russell S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2018
Onderwerpen:
Ivive and Toxicokinetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920326/
https://ncbi.nlm.nih.gov/pubmed/29385628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy020
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