Toxicokinetic Triage for Environmental Chemicals

Toxicokinetic (TK) models link administered doses to plasma, blood, and tissue concentrations. High-throughput TK (HTTK) performs in vitro to in vivo extrapolation to predict TK from rapid in vitro measurements and chemical structure-based properties. A significant toxicological application of HTTK...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Wambaugh, John F., Wetmore, Barbara A., Pearce, Robert, Strope, Cory, Goldsmith, Rocky, Sluka, James P., Sedykh, Alexander, Tropsha, Alex, Bosgra, Sieto, Shah, Imran, Judson, Richard, Thomas, Russell S., Woodrow Setzer, R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Computational Model to Prioritize Chemical Risk
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560038/
https://ncbi.nlm.nih.gov/pubmed/26085347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv118
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