Toxicokinetic Triage for Environmental Chemicals

Toxicokinetic (TK) models link administered doses to plasma, blood, and tissue concentrations. High-throughput TK (HTTK) performs in vitro to in vivo extrapolation to predict TK from rapid in vitro measurements and chemical structure-based properties. A significant toxicological application of HTTK...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Toxicol Sci
Prif Awduron: Wambaugh, John F., Wetmore, Barbara A., Pearce, Robert, Strope, Cory, Goldsmith, Rocky, Sluka, James P., Sedykh, Alexander, Tropsha, Alex, Bosgra, Sieto, Shah, Imran, Judson, Richard, Thomas, Russell S., Woodrow Setzer, R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2015
Pynciau:
Computational Model to Prioritize Chemical Risk
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560038/
https://ncbi.nlm.nih.gov/pubmed/26085347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv118
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