Toxicokinetic Triage for Environmental Chemicals

Toxicokinetic (TK) models link administered doses to plasma, blood, and tissue concentrations. High-throughput TK (HTTK) performs in vitro to in vivo extrapolation to predict TK from rapid in vitro measurements and chemical structure-based properties. A significant toxicological application of HTTK...

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Dades bibliogràfiques
Publicat a:Toxicol Sci
Autors principals: Wambaugh, John F., Wetmore, Barbara A., Pearce, Robert, Strope, Cory, Goldsmith, Rocky, Sluka, James P., Sedykh, Alexander, Tropsha, Alex, Bosgra, Sieto, Shah, Imran, Judson, Richard, Thomas, Russell S., Woodrow Setzer, R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Computational Model to Prioritize Chemical Risk
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560038/
https://ncbi.nlm.nih.gov/pubmed/26085347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv118
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