Učitavanje...
High throughput evaluation of macrocyclization strategies for conformer stabilization
While macrocyclization of a linear compound to stabilize a known bioactive conformation can be a useful strategy to increase binding potency, the difficulty of macrocycle synthesis can limit the throughput of such strategies. Thus computational techniques may offer the higher throughput required to...
Spremljeno u:
| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5920116/ https://ncbi.nlm.nih.gov/pubmed/29700331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24766-5 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|