Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma

During helminth infection and allergic asthma, naive CD4(+) T-cells differentiate into cytokine-producing Type-2 helper (Th2) cells that resolve the infection or induce asthma-associated pathology. Mechanisms regulating the Th2 differentiation in vivo remain poorly understood. Here we report that mi...

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Vydáno v:Nat Commun
Hlavní autoři: Lorentsen, Kyle J., Cho, Jonathan J., Luo, Xiaoping, Zuniga, Ashley N., Urban, Joseph F., Zhou, Liang, Gharaibeh, Raad, Jobin, Christian, Kladde, Michael P., Avram, Dorina
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920086/
https://ncbi.nlm.nih.gov/pubmed/29700302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04111-0
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