Cargando...
Role of Tyk-2 in Th9 and Th17 cells in allergic asthma
In a murine model of allergic asthma, we found that Tyk-2((−/−)) asthmatic mice have induced peribronchial collagen deposition, mucosal type mast cells in the lung, IRF4 and hyperproliferative lung Th2 CD4(+) effector T cells over-expressing IL-3, IL-4, IL-5, IL-10 and IL-13. We also observed increa...
Gardado en:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2014
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4127519/ https://ncbi.nlm.nih.gov/pubmed/25109392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05865 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|