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Immunoregulatory role of acid sphingomyelinase in allergic asthma

Acid sphingomyelinase (ASM) is one of the enzymes that catalyzes the breakdown of sphingomyelin to ceramide and phosphorylcholine. In this study, we aimed at elucidating the role of ASM in allergic asthma. We used an ovalbumin‐induced murine model of asthma where we compared wild‐type and ASM‐defici...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Sopel, Nina, Kölle, Julia, Dumendiak, Sonja, Koch, Sonja, Reichel, Martin, Rhein, Cosima, Kornhuber, Johannes, Finotto, Susetta
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418424/
https://ncbi.nlm.nih.gov/pubmed/30556232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13035
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