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Immunoregulatory role of acid sphingomyelinase in allergic asthma

Acid sphingomyelinase (ASM) is one of the enzymes that catalyzes the breakdown of sphingomyelin to ceramide and phosphorylcholine. In this study, we aimed at elucidating the role of ASM in allergic asthma. We used an ovalbumin‐induced murine model of asthma where we compared wild‐type and ASM‐defici...

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Bibliografiske detaljer
Udgivet i:Immunology
Main Authors: Sopel, Nina, Kölle, Julia, Dumendiak, Sonja, Koch, Sonja, Reichel, Martin, Rhein, Cosima, Kornhuber, Johannes, Finotto, Susetta
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418424/
https://ncbi.nlm.nih.gov/pubmed/30556232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.13035
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