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IL-17A is a central regulator of lung tumor growth

In a recent study we reported increased expression of IL-17A in the lung of patients with lung adenocarcinoma. Local blockade of IL-17A in the lung, in a model of lung cancer revealed enhanced anti-tumor immunity characterized by increased IFNγ, a diminished T-regulatory cell number and reduced tumo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Reppert, Sarah, Koch, Sonja, Finotto, Susetta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429594/
https://ncbi.nlm.nih.gov/pubmed/22934282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19735
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