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Synergistic Enhancement of Cisplatin Cytotoxicity by SN‐38, an Active Metabolite of CPT‐11, for Cisplatin‐resistant HeLa Cells

A cisplatin (cis‐diamininedichloroplatinuin(II); CDDP)‐resistant HeLa cell line (HeLa/CDDP cells), which showed more than 8‐fold resistance to CDDF compared to the parent cells, was newly established for this study. HeLa/CDDP cells accumulated 50% less platinum than the parent cells. There was no di...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Minagawa, Yukihisa, Kigawa, Junzo, Ishihara, Hiroshi, Itamochi, Hiroaki, Terakawa, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919584/
https://ncbi.nlm.nih.gov/pubmed/7961127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1994.tb02976.x
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