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Enhanced Topoisomerase I Activity and Increased Topoisomerase IIα Content in Cisplatin‐resistant Cancer Cell Lines

Although the combined effects of cisplatin (CDDP) and DNA topoisomerase (Topo) inhibitors have been described in recent literature, little is known about the combined effects and their biological basis in CDDP‐resistant cells. The aim of the present study was to elucidate the combined effect of CDDP...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Minagawa, Yukihisa, Kigawa, Junzo, Irie, Takashi, Kanamori, Yasunobu, Itamochi, Hiroaki, Cheng, Xiusi, Terakawa, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921345/
https://ncbi.nlm.nih.gov/pubmed/9473741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00352.x
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