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Megakaryocyte lineage development is controlled by modulation of protein acetylation

Treatment with lysine deacetylase inhibitors (KDACi) for haematological malignancies, is accompanied by haematological side effects including thrombocytopenia, suggesting that modulation of protein acetylation affects normal myeloid development, and specifically megakaryocyte development. In the cur...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Bartels, Marije, Govers, Anita, Polak, Roel, Vervoort, Stephin, van Boxtel, Ruben, Pals, Cornelieke, Bierings, Marc, van Solinge, Wouter, Egberts, Toine, Nieuwenhuis, Edward, Mokry, Michal, Coffer, Paul James
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919413/
https://ncbi.nlm.nih.gov/pubmed/29698469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196400
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