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SOX4 Mediates TGF-β-Induced Expression of Mesenchymal Markers during Mammary Cell Epithelial to Mesenchymal Transition

The epithelial to mensenchymal transition program regulates various aspects of embryonic development and tissue homeostasis, but aberrant activation of this pathway in cancer contributes to tumor progression and metastasis. TGF-β potently induces an epithelial to mensenchymal transition in cancers o...

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Detalhes bibliográficos
Main Authors: Vervoort, Stephin J., Lourenço, Ana Rita, van Boxtel, Ruben, Coffer, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536747/
https://ncbi.nlm.nih.gov/pubmed/23301048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053238
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