Megakaryocyte lineage development is controlled by modulation of protein acetylation

Treatment with lysine deacetylase inhibitors (KDACi) for haematological malignancies, is accompanied by haematological side effects including thrombocytopenia, suggesting that modulation of protein acetylation affects normal myeloid development, and specifically megakaryocyte development. In the cur...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bartels, Marije, Govers, Anita, Polak, Roel, Vervoort, Stephin, van Boxtel, Ruben, Pals, Cornelieke, Bierings, Marc, van Solinge, Wouter, Egberts, Toine, Nieuwenhuis, Edward, Mokry, Michal, Coffer, Paul James
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919413/
https://ncbi.nlm.nih.gov/pubmed/29698469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0196400
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