5′‐Deoxy‐S‐fluorouridine Increases Daunorubicin Uptake in Multidrug‐resistant Cells and Its Activity Is Related with P‐gp 170 Expression

Most anticancer agents fail to induce clear responses in the treatment of colorectal cancer. This can be explained by involvement of overexpression of the membrane glycoprotein, P‐gp 170, which is associated with multidrug resistance (MDR), and/or with involvement of ras. Fluoropyrimidines are among...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: van der Heyden, Sylke, Gheuens, Eric, van de Vrie, Wim, Van Bockstaele, Dirk, Van Oosterom, Allan, Eggermont, Alexander, De Bruijn, Ernst A.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1994
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919339/
https://ncbi.nlm.nih.gov/pubmed/7906263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1994.tb02880.x
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