DNA polymerase β: A missing link of the base excision repair machinery in mammalian mitochondria

Mitochondrial genome integrity is fundamental to mammalian cell viability. Since mitochondrial DNA is constantly under attack from oxygen radicals released during ATP production, DNA repair is vital in removing oxidatively generated lesions in mitochondrial DNA, but the presence of a strong base exc...

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Gepubliceerd in:DNA Repair (Amst)
Hoofdauteurs: Prasad, Rajendra, Çağlayan, Melike, Dai, Da-Peng, Nadalutti, Cristina A., Zhao, Ming-Lang, Gassman, Natalie R., Janoshazi, Agnes K., Stefanick, Donna F., Horton, Julie K., Krasich, Rachel, Longley, Matthew J., Copeland, William C., Griffith, Jack D., Wilson, Samuel H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919216/
https://ncbi.nlm.nih.gov/pubmed/29100041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.10.011
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