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A Let-7 MicroRNA SNP in the KRAS 3′UTR Is Prognostic in Early-Stage Colorectal Cancer

PURPOSE: Colorectal cancer (CRC) is a common cause of death worldwide. Tumor-node-metastasis-system stage is currently used to guide therapy decisions but lacks precision. Prognostic biomarkers are needed to refine stratification of patients for chemotherapy but validated biomarkers are not yet avai...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Smits, Kim M., Paranjape, Trupti, Nallur, Sunitha, Wouters, Kim A.D., Weijenberg, Matty P., Schouten, Leo J., van den Brandt, Piet A., Bosman, Fred T., Weidhaas, Joanne B., van Engeland, Manon
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919188/
https://ncbi.nlm.nih.gov/pubmed/21994416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0990
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