A SNP in a let-7 microRNA complementary site in the KRAS 3′UTR Increases Non-Small Cell Lung Cancer Risk

Lung cancer is the leading cause of cancer deaths worldwide, yet few genetic markers of lung cancer risk useful for screening exist. The let-7 family-of-microRNAs (miRNAs) are global genetic regulators important in controlling lung cancer oncogene expression by binding to the 3′UTRs (untranslated re...

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Hlavní autoři: Chin, Lena J., Ratner, Elena, Leng, Shuguang, Zhai, Rihong, Nallur, Sunitha, Babar, Imran, Muller, Roman-Ulrich, Straka, Eva, Su, Li, Burki, Elizabeth A., Crowell, Richard E., Patel, Rajeshvari, Kulkarni, Trupti, Homer, Robert, Zelterman, Daniel, Kidd, Kenneth K., Zhu, Yong, Christiani, David C., Belinsky, Steven A., Slack, Frank J., Weidhaas, Joanne B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672193/
https://ncbi.nlm.nih.gov/pubmed/18922928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2129
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