A SNP in a let-7 microRNA complementary site in the KRAS 3′UTR Increases Non-Small Cell Lung Cancer Risk

Lung cancer is the leading cause of cancer deaths worldwide, yet few genetic markers of lung cancer risk useful for screening exist. The let-7 family-of-microRNAs (miRNAs) are global genetic regulators important in controlling lung cancer oncogene expression by binding to the 3′UTRs (untranslated re...

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Detalhes bibliográficos
Main Authors: Chin, Lena J., Ratner, Elena, Leng, Shuguang, Zhai, Rihong, Nallur, Sunitha, Babar, Imran, Muller, Roman-Ulrich, Straka, Eva, Su, Li, Burki, Elizabeth A., Crowell, Richard E., Patel, Rajeshvari, Kulkarni, Trupti, Homer, Robert, Zelterman, Daniel, Kidd, Kenneth K., Zhu, Yong, Christiani, David C., Belinsky, Steven A., Slack, Frank J., Weidhaas, Joanne B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672193/
https://ncbi.nlm.nih.gov/pubmed/18922928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2129
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