A 3′-UTR KRAS-variant is associated with cisplatin resistance in patients with recurrent and/or metastatic head and neck squamous cell carcinoma

BACKGROUND: A germline mutation in the 3′-untranslated region of KRAS (rs61764370, KRAS-variant: TG/GG) has previously been associated with altered patient outcome and drug resistance/sensitivity in various cancers. We examined the prognostic and predictive significance of this variant in recurrent/...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Chung, C. H., Lee, J. W., Slebos, R. J., Howard, J. D., Perez, J., Kang, H., Fertig, E. J., Considine, M., Gilbert, J., Murphy, B. A., Nallur, S., Paranjape, T., Jordan, R. C., Garcia, J., Burtness, B., Forastiere, A. A., Weidhaas, J. B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Soggetti:
Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207729/
https://ncbi.nlm.nih.gov/pubmed/25081901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdu367
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi