Investigation of sirtuin 1 polymorphisms in relation to the risk of colorectal cancer by molecular subtype

Sirtuin 1 (SIRT1), a histone deacetylase, is involved in maintenance of genetic stability, inflammation, immune response, metabolism (energy-sensing molecule) and colorectal tumorigenesis. We investigated SIRT1’s specific role in colorectal tumorigenesis by studying SIRT1 polymorphisms in relation t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hrzic, Rok, Simons, Colinda C. J. M., Schouten, Leo J., van Engeland, Manon, Brandt, Piet van den, Weijenberg, Matty P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042277/
https://ncbi.nlm.nih.gov/pubmed/32098999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60300-2
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