Genetic Variants in the Insulin-like Growth Factor Pathway and Colorectal Cancer Risk in the Netherlands Cohort Study

Interrelationships between insulin-like growth factors (IGFs), hyperinsulinaemia, diabetes, and colorectal cancer (CRC) indicate involvement of IGFs in colorectal tumorigenesis. We investigated the CRC risk associated with 24 single nucleotide polymorphisms (SNPs) in 9 genes related to the IGF pathw...

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Publicado no:Sci Rep
Main Authors: Simons, Colinda C. J. M., Schouten, Leo J., Godschalk, Roger W. L., van Engeland, Manon, van den Brandt, Piet A., van Schooten, Frederik J., Weijenberg, Matty P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585376/
https://ncbi.nlm.nih.gov/pubmed/26381944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14126
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