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Ubiquitous Presence in Mammalian Cells of Enzymatic Activity Specifically Cleaving 8‐Hydroxyguanine‐containing DNA
Here we report the finding of enzymatic activity that specifically cleaves DNA containing 8‐hydroxyguanine (oh(8)Gua) residues in various mammalian cells. To detect this activity, we used a synthetic double‐stranded DNA containing a single oh(8)Gua at a defined position as the substrate, and analyze...
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| Publicado no: | Jpn J Cancer Res |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5918833/ https://ncbi.nlm.nih.gov/pubmed/1506269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb00114.x |
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