Comparison of Incorporation and Extension of Nucleotides in vitro opposite 8‐Hydroxyguanine (7,8‐Dihydro‐8‐oxoguanine) in Hot Spots of the c‐Ha‐ras Gene

DNA templates with 8‐hydroxyguanine (7,8‐dihydro‐8‐oxoguanine, oh(8)Gua) at a site corresponding to the first or second position of codon 12 of the c‐Ha‐ras gene were prepared, and the nucleotides inserted opposite the modified base were compared. The Klenow fragment (KF) of Escherichia coli DNA pol...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Kamiya, Hiroyuki, Murata‐Kamiya, Naoko, Fujimuro, Masahiro, Kido, Kaori, Inoue, Hideo, Nishimura, Susumu, Masutani, Chikahide, Hanaoka, Fumio, Ohtsuka, Eiko
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1995
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920815/
https://ncbi.nlm.nih.gov/pubmed/7744697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1995.tb03050.x
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