What causes human cancer? Approaches from the chemistry of DNA damage

door Kasai, Hiroshi
Gepubliceerd in Genes Environ (2016)

2-Hydroxy-dATP is incorporated opposite G by Escherichia coli DNA polymerase III resulting in high mutagenicity

door Kamiya, Hiroyuki, Kasai, Hiroshi
Gepubliceerd in 2000

New Plausible Mechanism for Gastric and Colorectal Carcinogenesis: Free Radical-Mediated Acetaldehyde Generation in a Heme/Myoglobin–Linoleate–Ethanol Mixture

door Kasai, Hiroshi, Kawai, Kazuaki
Gepubliceerd in ACS Omega (2021)

Free radical-mediated acetaldehyde formation by model reactions of dietary components: effects of meat, wine, cooking oil and coffee

door Kasai, Hiroshi, Kawai, Kazuaki
Gepubliceerd in Genes Environ (2021)

Analysis of Cytosolic Phosphoethanolamine and Ethanolamine and Their Correlation with Prognostic Factors in Breast Cancer

door Kano‐Sueoka, Tamiko, Watanabe, Toru, Miya, Toshimichi, Kasai, Hiroshi
Gepubliceerd in Jpn J Cancer Res (1991)

Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2-hydroxy-ATP

door Fujikawa, Katsuyoshi, Kamiya, Hiroyuki, Yakushiji, Hiroyuki, Nakabeppu, Yusaku, Kasai, Hiroshi
Gepubliceerd in 2001

Metal nanoparticle-induced micronuclei and oxidative DNA damage in mice

door Song, Ming-Fen, Li, Yun-Shan, Kasai, Hiroshi, Kawai, Kazuaki
Gepubliceerd in 2012

Thermodynamic stability of base pairs between 2-hydroxyadenine and incoming nucleotides as a determinant of nucleotide incorporation specificity during replication

door Kawakami, Junji, Kamiya, Hiroyuki, Yasuda, Kyohko, Fujiki, Hiroyoshi, Kasai, Hiroshi, Sugimoto, Naoki
Gepubliceerd in 2001

Psychosocial Factors as a Potential Trigger of Oxidative DNA Damage in Human Leukocytes

door Irie, Masahiro, Asami, Shinya, Nagata, Shoji, Ikeda, Masato, Miyata, Masakazu, Kasai, Hiroshi
Gepubliceerd in Jpn J Cancer Res (2001)

Elevated Level of 8‐Hydroxydeoxyguanosine in DNA of Liver, Kidneys, and Brain of Long‐Evans Cinnamon Rats

door Yamamoto, Fuyumi, Kasai, Hiroshi, Togashi, Yuji, Takeichi, Noritoshi, Hori, Tomokatsu, Nishimura, Susumu
Gepubliceerd in Jpn J Cancer Res (1993)

Lung Cancer Patients Have Increased 8‐Hydroxydeoxyguanosine Levels in Peripheral Lung Tissue DNA

door Inoue, Masaaki, Osaki, Toshihiro, Noguchi, Masayuki, Hirohashi, Setsuo, Yasumoto, Kosei, Kasai, Hiroshi
Gepubliceerd in Jpn J Cancer Res (1998)

Infrequent Mutations of the hOGG1 Gene, That Is Involved in the Excision of 8‐Hydroxyguanine in Damaged DNA, in Human Gastric Cancer

door Shinmura, Kazuya, Kohno, Takashi, Kasai, Hiroshi, Koda, Kenji, Sugimura, Haruhiko, Yokota, Jun
Gepubliceerd in Jpn J Cancer Res (1998)

Increase in 8‐Hydroxyguanine and Its Repair Activity in the Esophagi of Rats Given Long‐term Ethanol and Nutrition‐deficient Diet

door Asami, Shinya, Hirano, Takeshi, Yamaguchi, Raizo, Tsurudome, Yosuke, Itoh, Hideaki, Kasai, Hiroshi
Gepubliceerd in Jpn J Cancer Res (2000)

Comparison of Blueberry (Vaccinium spp.) and Vitamin C via Antioxidative and Epigenetic Effects in Human

door Kim, Minju, Na, Hyunkyung, Kasai, Hiroshi, Kawai, Kazuaki, Li, Yun-Shan, Yang, Mihi
Gepubliceerd in J Cancer Prev (2017)

Diurnal and day-to-day variation of urinary oxidative stress marker 8-hydroxy-2'-deoxyguanosine

door Li, Yun-Shan, Kawasaki, Yuya, Watanabe, Sintaroo, Ootsuyama, Yuko, Kasai, Hiroshi, Kawai, Kazuaki
Gepubliceerd in J Clin Biochem Nutr (2021)

An oxidized nucleotide affects DNA replication through activation of protein kinases in Xenopus egg lysates

door Kai, Toshinori, Matsunaga, Rieko, Eguchi, Masami, Kamiya, Hiroyuki, Kasai, Hiroshi, Suzuki, Motoshi, Izuta, Shunji
Gepubliceerd in 2002

Lower serum levels of total cholesterol are associated with higher urinary levels of 8-hydroxydeoxyguanosine

door Kikuchi, Hiroyuki, Nanri, Akiko, Hori, Ai, Sato, Masao, Kawai, Kazuaki, Kasai, Hiroshi, Mizoue, Tetsuya
Gepubliceerd in 2013

Analyses of Oxidative DNA Damage and Its Repair Activity in the Livers of 3′‐Methyl‐4‐dimethylaminoazobenzene‐treated Rodents

door Hirano, Takeshi, Higashi, Ken, Sakai, Akinori, Tsurudome, Yosuke, Ootsuyama, Yuko, RieKido, Kasai, Hiroshi
Gepubliceerd in Jpn J Cancer Res (2000)

Life Style and Urinary 8‐Hydroxydeoxyguanosine, a Marker of Oxidative DNA Damage: Effects of Exercise, Working Conditions, Meat Intake, Body Mass Index, and Smoking

door Kasai, Hiroshi, Iwamoto‐Tanaka, Naoko, Miyamoto, Toshiaki, Kawanami, Kiyoshi, Kawanami, Shoko, Kido, Rie, Ikeda, Masato
Gepubliceerd in Jpn J Cancer Res (2001)

Novel mechanism of post-transcriptional modification of tRNA: insertion of base of Q precursor into tRNA by tRNA transglycosidase reaction

door Okada, Norihiro, Noguchi, Shigeru, Kasai, Hiroshi, Shindo-Okada, Nobuko, Ohgi, Tadaaki, Goto, Toshio, Nishimura, Susumu
Gepubliceerd in Nucleic Acids Res (1978)