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Infrequent Mutations of the hOGG1 Gene, That Is Involved in the Excision of 8‐Hydroxyguanine in Damaged DNA, in Human Gastric Cancer

DNA glycosylase, encoded by the hOGG1 gene, repairs 8‐hydroxyguanine (oh(8)Gua), which is an oxidatively damaged mutagenic base. To clarify whether the DNA repair activity of hOGG1 protein is involved in gastric carcinogenesis, we examined 9 gastric cancer cell lines and 35 primary gastric cancers f...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Shinmura, Kazuya, Kohno, Takashi, Kasai, Hiroshi, Koda, Kenji, Sugimura, Haruhiko, Yokota, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921916/
https://ncbi.nlm.nih.gov/pubmed/9765618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb00635.x
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