Thermodynamic stability of base pairs between 2-hydroxyadenine and incoming nucleotides as a determinant of nucleotide incorporation specificity during replication

We investigated the thermodynamic stability of double-stranded DNAs with an oxidative DNA lesion, 2-hydroxyadenine (2-OH-Ade), in two different sequence contexts (5′-GA*C-3′ and 5′-TA*A-3′, A* represents 2-OH-Ade). When an A*–N pair (N, any nucleotide base) was located in the center of a duplex, the...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Kawakami, Junji, Kamiya, Hiroyuki, Yasuda, Kyohko, Fujiki, Hiroyoshi, Kasai, Hiroshi, Sugimoto, Naoki
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55858/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11504865/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.16.3289
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