Ubiquitous Presence in Mammalian Cells of Enzymatic Activity Specifically Cleaving 8‐Hydroxyguanine‐containing DNA

Here we report the finding of enzymatic activity that specifically cleaves DNA containing 8‐hydroxyguanine (oh(8)Gua) residues in various mammalian cells. To detect this activity, we used a synthetic double‐stranded DNA containing a single oh(8)Gua at a defined position as the substrate, and analyze...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Yamamoto, Fuyumi, Kasai, Hiroshi, Bessho, Tadayoshi, Chung, Myung‐Hee, Inoue, Hideo, Ohtsuka, Eiko, Hori, Tomokatsu, Nishimura, Susumu
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1992
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918833/
https://ncbi.nlm.nih.gov/pubmed/1506269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb00114.x
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