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Exact association test for small size sequencing data

BACKGROUND: Recent statistical methods for next generation sequencing (NGS) data have been successfully applied to identifying rare genetic variants associated with certain diseases. However, most commonly used methods (e.g., burden tests and variance-component tests) rely on large sample sizes. Not...

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發表在:BMC Med Genomics
Main Authors: Lee, Joowon, Lee, Seungyeoun, Jang, Jin-Young, Park, Taesung
格式: Artigo
語言:Inglês
出版: BioMed Central 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918458/
https://ncbi.nlm.nih.gov/pubmed/29697368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0344-z
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