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Exact association test for small size sequencing data

BACKGROUND: Recent statistical methods for next generation sequencing (NGS) data have been successfully applied to identifying rare genetic variants associated with certain diseases. However, most commonly used methods (e.g., burden tests and variance-component tests) rely on large sample sizes. Not...

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Bibliografiska uppgifter
I publikationen:BMC Med Genomics
Huvudupphovsmän: Lee, Joowon, Lee, Seungyeoun, Jang, Jin-Young, Park, Taesung
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918458/
https://ncbi.nlm.nih.gov/pubmed/29697368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0344-z
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