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Exact association test for small size sequencing data

BACKGROUND: Recent statistical methods for next generation sequencing (NGS) data have been successfully applied to identifying rare genetic variants associated with certain diseases. However, most commonly used methods (e.g., burden tests and variance-component tests) rely on large sample sizes. Not...

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Foilsithe in:BMC Med Genomics
Main Authors: Lee, Joowon, Lee, Seungyeoun, Jang, Jin-Young, Park, Taesung
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918458/
https://ncbi.nlm.nih.gov/pubmed/29697368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0344-z
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