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Exact association test for small size sequencing data

BACKGROUND: Recent statistical methods for next generation sequencing (NGS) data have been successfully applied to identifying rare genetic variants associated with certain diseases. However, most commonly used methods (e.g., burden tests and variance-component tests) rely on large sample sizes. Not...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Lee, Joowon, Lee, Seungyeoun, Jang, Jin-Young, Park, Taesung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918458/
https://ncbi.nlm.nih.gov/pubmed/29697368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0344-z
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