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Amplification of CD20 Cross-Linking in Rituximab-Resistant B-Lymphoma Cells Enhances Apoptosis Induction by Drug-Free Macromolecular Therapeutics

Although the CD20-targeted monoclonal antibody rituximab (RTX) has revolutionized the therapeutic landscape for B-cell malignancy, relapsed and refractory disease due to RTX resistance continue to constitute major challenges, illustrating the need for better therapies. Here, we apply drug-free macro...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Li, Lian, Yang, Jiyuan, Wang, Jiawei, Kopeček, Jindřich
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916500/
https://ncbi.nlm.nih.gov/pubmed/29595951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b00797
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