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Drug-Free Macromolecular Therapeutics Induce Apoptosis via Calcium Influx and Mitochondrial Signaling Pathway

Recently, an innovative paradigm has been proposed in macromolecular therapeutics for treatment of B-cell lymphomas that can specifically kill cancer cells without a drug. The design rationale of this drug-free macromolecular therapeutic (DFMT) system is crosslinking the cell surface receptor to ini...

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Detalhes bibliográficos
Publicado no:Macromol Biosci
Main Authors: Li, Lian, Yang, Jiyuan, Wang, Jiawei, Kopeček, Jindřich
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5912161/
https://ncbi.nlm.nih.gov/pubmed/28805013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201700196
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