PTEN deficiency promotes pathological vascular remodeling of human coronary arteries

Phosphatase and tensin homolog (PTEN) is an essential regulator of the differentiated vascular smooth muscle cell (SMC) phenotype. Our goal was to establish that PTEN loss promotes SMC dedifferentiation and pathological vascular remodeling in human atherosclerotic coronary arteries and nonatheroscle...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Moulton, Karen S., Li, Marcella, Strand, Keith, Burgett, Shawna, McClatchey, Penn, Tucker, Rebecca, Furgeson, Seth B., Lu, Sizhao, Kirkpatrick, Bruce, Cleveland, Joseph C., Nemenoff, Raphael A., Ambardekar, Amrut V., Weiser-Evans, Mary C.M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916252/
https://ncbi.nlm.nih.gov/pubmed/29467331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97228
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