PTEN deficiency promotes pathological vascular remodeling of human coronary arteries

Phosphatase and tensin homolog (PTEN) is an essential regulator of the differentiated vascular smooth muscle cell (SMC) phenotype. Our goal was to establish that PTEN loss promotes SMC dedifferentiation and pathological vascular remodeling in human atherosclerotic coronary arteries and nonatheroscle...

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Publicat a:JCI Insight
Autors principals: Moulton, Karen S., Li, Marcella, Strand, Keith, Burgett, Shawna, McClatchey, Penn, Tucker, Rebecca, Furgeson, Seth B., Lu, Sizhao, Kirkpatrick, Bruce, Cleveland, Joseph C., Nemenoff, Raphael A., Ambardekar, Amrut V., Weiser-Evans, Mary C.M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916252/
https://ncbi.nlm.nih.gov/pubmed/29467331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97228
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