The NLRP3-Caspase 1 Inflammasome Negatively Regulates Autophagy via TLR4-TRIF in Prion Peptide-Infected Microglia

Prion diseases are neurodegenerative disorders characterized by the accumulation of misfolded prion protein, spongiform changes in the brain, and brain inflammation as a result of the wide-spread activation of microglia. Autophagy is a highly conserved catabolic process for the clearance of cytoplas...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Front Aging Neurosci
Huvudupphovsmän: Lai, Mengyu, Yao, Hao, Shah, Syed Zahid Ali, Wu, Wei, Wang, Di, Zhao, Ying, Wang, Lu, Zhou, Xiangmei, Zhao, Deming, Yang, Lifeng
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915529/
https://ncbi.nlm.nih.gov/pubmed/29720937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00116
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk