Role of GM-CSF in the inflammatory cytokine network that regulates neutrophil influx into the colonic mucosa during Clostridium difficile infection in mice

Clostridium difficile infection in antibiotic-treated mice results in acute colitis characterized by severe intestinal histopathology, robust neutrophil influx, and increased expression of numerous inflammatory cytokines, including GM-CS F. We utilized a neutralizing monoclonal antibody (mAb) agains...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Gut Microbes
Prif Awduron: McDermott, Andrew J, Frank, Charles R, Falkowski, Nicole R, McDonald, Roderick A, Young, Vincent B, Huffnagle, Gary B
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915364/
https://ncbi.nlm.nih.gov/pubmed/25045999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.29964
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