Role of GM-CSF in the inflammatory cytokine network that regulates neutrophil influx into the colonic mucosa during Clostridium difficile infection in mice

Clostridium difficile infection in antibiotic-treated mice results in acute colitis characterized by severe intestinal histopathology, robust neutrophil influx, and increased expression of numerous inflammatory cytokines, including GM-CS F. We utilized a neutralizing monoclonal antibody (mAb) agains...

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I publikationen:Gut Microbes
Huvudupphovsmän: McDermott, Andrew J, Frank, Charles R, Falkowski, Nicole R, McDonald, Roderick A, Young, Vincent B, Huffnagle, Gary B
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915364/
https://ncbi.nlm.nih.gov/pubmed/25045999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.29964
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