The role of Gr-1(+) cells and tumour necrosis factor-α signalling during Clostridium difficile colitis in mice

The host response to Clostridium difficile infection in antibiotic-treated mice is characterized by robust recruitment of Gr-1(+) cells, increased expression of inflammatory cytokines including tumour necrosis factor-α (TNF-α), and the development of severe epithelial damage. To investigate the role...

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Publicado no:Immunology
Main Authors: McDermott, Andrew J, Higdon, Kathryn E, Muraglia, Ryan, Erb-Downward, John R, Falkowski, Nicole R, McDonald, Roderick A, Young, Vincent B, Huffnagle, Gary B
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368176/
https://ncbi.nlm.nih.gov/pubmed/25399934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12425
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