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Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response

The current study sought to delineate the gene expression profile of the host response in the caecum and colon during acute infection with Clostridium difficile in a mouse model of infection, and to investigate the nature of the unfolded protein response in this process. The infected mice displayed...

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Detalhes bibliográficos
Main Authors: Sadighi Akha, Amir A, Theriot, Casey M, Erb-Downward, John R, McDermott, Andrew J, Falkowski, Nicole R, Tyra, Heather M, Rutkowski, D Thomas, Young, Vincent B, Huffnagle, Gary B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809711/
https://ncbi.nlm.nih.gov/pubmed/23668260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12122
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