Role of interferon‐γ and inflammatory monocytes in driving colonic inflammation during acute Clostridium difficile infection in mice

The inflammatory response to the colonic pathogen Clostridium difficile is characterized by the induction of inflammatory cytokines including Interleukin‐23 (IL‐23) and interferon‐γ (IFN‐γ) and the recruitment of myeloid cells including Ly6C(H) (igh) monocytes. IL‐23 knockout mice showed reduced exp...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: McDermott, Andrew J., Falkowski, Nicole R., McDonald, Roderick A., Frank, Charles R., Pandit, Chinmay R., Young, Vincent B., Huffnagle, Gary B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343354/
https://ncbi.nlm.nih.gov/pubmed/27995603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12700
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