Improvement of non-alcoholic steatohepatitis by hepatocyte-like cells generated from iPSCs with Oct4/Sox2/Klf4/Parp1

The prevalence of nonalcoholic fatty liver disease (NAFLD) is usually increased with age. Non-alcoholic steatohepatitis (NASH), a serious form of NAFLD, may lead to cirrhosis and end-stage liver diseases. Induced pluripotent stem cells (iPSCs) hold promising potential in personalized medicine. Altho...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Chien, Yueh, Huang, Chi-Shuan, Lin, Hsin-Chi, Lu, Kai-Hsi, Tsai, Ping-Hsing, Lai, Ying-Hsiu, Chen, Kuan-Hsuan, Lee, Shou-Dong, Huang, Yi-Hsiang, Wang, Chien-Ying
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2018
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915096/
https://ncbi.nlm.nih.gov/pubmed/29719629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23603
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