Ligand-dependent transcriptional induction of lethal autophagy: A new perspective for cancer treatment

Dendrogenin A (DDA) is a mammalian metabolite that displays anticancer and chemopreventive properties in mice. At the cancer cell level, DDA induces differentiation and death. We investigated herein the nature of DDA cytoxicity in cancer cells. We showed that DDA triggers biochemical and cellular fe...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Silvente-Poirot, Sandrine, Segala, Gregory, Poirot, Mathias C., Poirot, Marc
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Autophagic Puncta
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915042/
https://ncbi.nlm.nih.gov/pubmed/29368971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1425059
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