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Ligand-dependent transcriptional induction of lethal autophagy: A new perspective for cancer treatment

Dendrogenin A (DDA) is a mammalian metabolite that displays anticancer and chemopreventive properties in mice. At the cancer cell level, DDA induces differentiation and death. We investigated herein the nature of DDA cytoxicity in cancer cells. We showed that DDA triggers biochemical and cellular fe...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Silvente-Poirot, Sandrine, Segala, Gregory, Poirot, Mathias C., Poirot, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5915042/
https://ncbi.nlm.nih.gov/pubmed/29368971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1425059
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