MULTIPLEXED ELIMINATION OF WILD-TYPE DNA AND HIGH RESOLUTION MELTING PRIOR TO TARGETED RESEQUENCING OF LIQUID BIOPSIES

BACKGROUND: The use of clinical samples and circulating cell free DNA (cfDNA) collected from liquid biopsies for diagnostic and prognostic applications in cancer is burgeoning, and improved methods that reduce the influence of excess wild-type (WT) portion of the sample are desirable. Here we presen...

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Publicat a:Clin Chem
Autors principals: Ladas, Ioannis, Fitarelli-Kiehl, Mariana, Song, Chen, Adalsteinsson, Viktor A., Parsons, Heather A., Lin, Nancy U., Wagle, Nikhil, Makrigiorgos, G. Mike
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914173/
https://ncbi.nlm.nih.gov/pubmed/28679646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2017.272849
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