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MULTIPLEXED ELIMINATION OF WILD-TYPE DNA AND HIGH RESOLUTION MELTING PRIOR TO TARGETED RESEQUENCING OF LIQUID BIOPSIES

BACKGROUND: The use of clinical samples and circulating cell free DNA (cfDNA) collected from liquid biopsies for diagnostic and prognostic applications in cancer is burgeoning, and improved methods that reduce the influence of excess wild-type (WT) portion of the sample are desirable. Here we presen...

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Bibliografski detalji
Izdano u:Clin Chem
Glavni autori: Ladas, Ioannis, Fitarelli-Kiehl, Mariana, Song, Chen, Adalsteinsson, Viktor A., Parsons, Heather A., Lin, Nancy U., Wagle, Nikhil, Makrigiorgos, G. Mike
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914173/
https://ncbi.nlm.nih.gov/pubmed/28679646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2017.272849
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