MULTIPLEXED ELIMINATION OF WILD-TYPE DNA AND HIGH RESOLUTION MELTING PRIOR TO TARGETED RESEQUENCING OF LIQUID BIOPSIES

BACKGROUND: The use of clinical samples and circulating cell free DNA (cfDNA) collected from liquid biopsies for diagnostic and prognostic applications in cancer is burgeoning, and improved methods that reduce the influence of excess wild-type (WT) portion of the sample are desirable. Here we presen...

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Détails bibliographiques
Publié dans:Clin Chem
Auteurs principaux: Ladas, Ioannis, Fitarelli-Kiehl, Mariana, Song, Chen, Adalsteinsson, Viktor A., Parsons, Heather A., Lin, Nancy U., Wagle, Nikhil, Makrigiorgos, G. Mike
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914173/
https://ncbi.nlm.nih.gov/pubmed/28679646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2017.272849
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