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SRC-like adaptor protein 2 (SLAP2) is a negative regulator of KIT-D816V-mediated oncogenic transformation

KIT is a receptor tyrosine kinase (RTK) involved in several cellular processes such as regulation of proliferation, survival and differentiation of early hematopoietic cells, germ cells and melanocytes. Activation of KIT results in phosphorylation of tyrosine residues in the receptor, and recruitmen...

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Publicat a:Sci Rep
Autors principals: Rupar, Kaja, Moharram, Sausan A., Kazi, Julhash U., Rönnstrand, Lars
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913247/
https://ncbi.nlm.nih.gov/pubmed/29686302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24743-y
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