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SRC-like adaptor protein 2 (SLAP2) is a negative regulator of KIT-D816V-mediated oncogenic transformation

KIT is a receptor tyrosine kinase (RTK) involved in several cellular processes such as regulation of proliferation, survival and differentiation of early hematopoietic cells, germ cells and melanocytes. Activation of KIT results in phosphorylation of tyrosine residues in the receptor, and recruitmen...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Rupar, Kaja, Moharram, Sausan A., Kazi, Julhash U., Rönnstrand, Lars
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913247/
https://ncbi.nlm.nih.gov/pubmed/29686302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24743-y
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