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SRC-like adaptor protein 2 (SLAP2) is a negative regulator of KIT-D816V-mediated oncogenic transformation

KIT is a receptor tyrosine kinase (RTK) involved in several cellular processes such as regulation of proliferation, survival and differentiation of early hematopoietic cells, germ cells and melanocytes. Activation of KIT results in phosphorylation of tyrosine residues in the receptor, and recruitmen...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rupar, Kaja, Moharram, Sausan A., Kazi, Julhash U., Rönnstrand, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913247/
https://ncbi.nlm.nih.gov/pubmed/29686302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24743-y
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