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Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling
Fms-like tyrosine kinase (FLT3) is a frequently mutated oncogene in acute myeloid leukemia (AML). FLT3 inhibitors display promising results in a clinical setting, but patients relapse after short-term treatment due to the development of resistant disease. Therefore, a better understanding of FLT3 do...
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| Yayımlandı: | Oncotarget |
|---|---|
| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Impact Journals LLC
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5295388/ https://ncbi.nlm.nih.gov/pubmed/27458164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10760 |
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