Expression of GADS enhances FLT3-induced mitogenic signaling

GADS is a member of a family of SH2 and SH3 domain-containing adaptors that functions in tyrosine kinase-mediated signaling cascades. Its expression is largely restricted to hematopoietic tissues and cell lines. Therefore, GADS is mainly involved in leukocyte-specific protein tyrosine kinase signali...

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Опубликовано в: :Oncotarget
Главные авторы: Chougule, Rohit A., Cordero, Eugenia, Moharram, Sausan A., Pietras, Kristian, Rönnstrand, Lars, Kazi, Julhash U.
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924701/
https://ncbi.nlm.nih.gov/pubmed/26895103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7415
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