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Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling

The suppressor of cytokine signaling 2 (SOCS2) is a member of the SOCS family of E3 ubiquitin ligases. SOCS2 is known to regulate signal transduction by cytokine receptors and receptor tyrosine kinases. The receptor tyrosine kinase FLT3 is of importance for proliferation, survival and differentiatio...

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Podrobná bibliografie
Vydáno v:Mol Oncol
Hlavní autoři: Kazi, Julhash U., Rönnstrand, Lars
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528470/
https://ncbi.nlm.nih.gov/pubmed/23548639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.02.020
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