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Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling

The suppressor of cytokine signaling 2 (SOCS2) is a member of the SOCS family of E3 ubiquitin ligases. SOCS2 is known to regulate signal transduction by cytokine receptors and receptor tyrosine kinases. The receptor tyrosine kinase FLT3 is of importance for proliferation, survival and differentiatio...

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Publicado en:Mol Oncol
Main Authors: Kazi, Julhash U., Rönnstrand, Lars
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528470/
https://ncbi.nlm.nih.gov/pubmed/23548639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2013.02.020
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